Want to Have a Candida Antibodies Test With ImuPro?

Candida antibodies tests are necessary to determine if the body needs any external medications to recover from fungal infection. The pathogen has the ability to self-stabilise itself and not allow the gut microbiota to recover and re-establish the normal metabolic environment. It consolidates its position in the digestive tract and further damages the inner lining resulting in the release of food and other particles into the blood stream. The leaked gut is the primary reason for food intolerance and build-up of gas and subsequent complications.

The type of treatment to be prescribed depends on finding how the body’s immune system is tackling the problem. Measuring the presence of immunoglobulin proteins such as IgG in the gut flora help establish the answer to this question and ascertain the treatment measures to be taken to address the proliferation. A chronic case such as Candidiasis where the fungi has permeated into the mucosal tissues increases the level of IgA, IgG and IgM antibodies. In such instances, their levels are found to be considerably higher than what would have been under normal circumstances.

All Candida related antibody and antigen tests should be checked by a practising physician and evaluated in relation to the person’s medical history. As in the case of all tests, the results are dependent on various factors such as past infections, the presence of the protein in the affected tissues and many more. For instance in the case of IgG, the tests would not be positive in case the person is suffering from illness and already has a high incidence of the antibodies in his serum. In certain cases, the IgG may persist several years after the infection has been completely eradicated. This is mostly due to the immunoglobulin’s ability to persist for a long period of time.

IgA is predominant in the mucosal tissues though it represents less than 20% of the proteins found in the human serum. A high incidence of IgA can be associated with mucosal epithelial, tracheobronchial, and genito-urinary infections of Candida. IgM is found in the intravascular cells and is the predominant immunoglobulin in early infections. Later illnesses may show a lesser level of this antibody as compared to the earlier ones. Besides these testing that may or may not prove a positive, antigen checks help determine if the proliferation has overwhelmed the gut flora. The presence of Candida antigen in the serum is a very positive indicator that the fungi has already entrenched itself in the gut. However, the absence of the antigen is an indeterminate result and cannot be taken as a positive sign that indicates the absence of the pathogen.

An ImuPro test helps to find all the allergies that affect patients. ImuPro tests analyse the patient’s reaction to over 271 food varieties and help clearly define the sources of any allergy.

Idiopathic Thrombocytopenic Purpura – Is Anti-D Antibody the Right ITP Treatment For You?

One form of ITP treatment is Anti-D Anti-body. This is just one of the conventional medical treatments doctors prescribe for idiopathic Thrombocytopenic Purpura (an autoimmune disease where the body destroys it’s own blood platelets. Marketed under the names of WinRho SDF or Rhophylac, Anti-D Antibody is a blood product used to raise the blood platelet count temporarily and occasionally longer term. In one study it was found to be effective about 80% of the time although the effects were temporary. the effects usually last about a month. Just what is Anti-D you might ask?. It is a freeze dried gamma globulin fraction which contains antibodies to Rh (D). It is made of human plasma from a limited list of donors. The plasma undergoes a viral inactivation and micro filtering process using a solvent detergent.

The donors are stimulated to produce Immunoglobulin with high levels of specific antibodies, thereby reducing the cost of the treatment by at least half of what IVIg treatment would cost. It is also safer to use then IVIg , because Anti-D has been treated to inactivate any form of viral contamination. Because Anti-D antibodies and action are so specific, it is only effective for people who still have their spleen and are Rh positive (about 85% of population). It may not be suitable for some pregnant women. Anti-D Antibody is taken either through an IV drip, which usually takes about half an hour or through an IV push, which just as the term indicates, pushes the infusion through your blood stream in about 5 minutes. These treatments can be given as a single dose or 2 doses over separate days. The frequency and dose is determined by the patient’s clinical response.

What are the side effects? Not pleasant to be sure and sometimes even deadly. They range from headaches, chills, fever and body aches, pain and swelling at the injection site. Not everyone experiences the same side effects. For people sensitive to blood products there is a remote risk of shock.. Anemia is also a problem because of the destruction of red blood cells. Monitoring the patient is especially important for people with low hemoglobin. Sometimes rare but serious complications such as intravascular hemolysis can occur which is releases hemoglobin into the plasma and involves pre-mature destruction of the red blood cells, and can result in death. Patients should be advised of warning signs for intravascular hemolysis such as back pain, shaking chills, fever, discolored urine, fluid retention, decreased urine, shortness of breath and sudden weight gain.

If you have ITP disorder and your physician has recommended Anti-D Antibody you should discuss all aspects of treatment with him, especially potential side effects in order to make the right decision about your health.

It seems like an awful lot of risk for a temporary fix. Don’t you think? Consider the risks and look for safer alternatives.

Antibody Engineering For Specific Application

Nowadays pharmaceutical and medicinal biotechnology is an improved section of biotechnology. Production of different developed drugs, vaccines, artificial insulin, etc. are achievements of this section. Antibody engineering is one of the most developed parts of medicinal biotechnology. If an antibody is modified due to a specific application through recombinant DNA technology then it is called antibody engineering. It is also called hybrid antibody or recombinant antibody.

Some steps which are essential for doing antibody engineering are-

1. Development of a design that will prepare the antibody to be used for a specific application that means by which it will bind with a specific antigen.

2. Accumulation of all the DNA sequences that would generate this antibody into a suitable expression vector

3. Introduction of a vector in a myeloma cell line so that the modified antibody gene can express itself

4. Mass culture of the transfected clones containing modified antibody genes of myeloma cell line

5. Harvesting the produced recombinant antibodies. But it should be noticed that the myeloma cell line would not produce any antibody of its own.

Monoclonal antibody that is being used widely as therapeutic agent has been produced by using antibody engineering. For producing monoclonal antibody a myeloma cell line is fused with spleen cell line of mouse which has already immunized with the desired antigen. In this HAT medium is used as culture medium because it contain hypoxanthine, thymine and aminopterin. Unfused hybridoma cell cannot grow in HAT medium due to lack of HGPRT and unfused spleen cell cannot grow infinitely because they have limited life span. After producing monoclonal antibody it is purified by western blotting system. Now a day’s monoclonal antibodies are widely being used in cancer treatment. It is also used for treating autoimmune diseases like infliximab, adalimumab.

Long Term Space Flight and Human Biosystem Antibodies – Deal Breaker or Is There a Solution?

NASA’s Astrobiological division certainly has some bugs to work out, literally with long-term human spaceflight. If we are going to create 100-years spaceship, and boldly travel to places that no human has ever been, then obviously we need to keep those humans alive for the duration of that trip. There are so many challenges involved it seems a bit overwhelming, but maybe it’s not, maybe we just aren’t thinking this through properly. Yes, we have the best minds in the business working on it, but maybe they aren’t thinking outside the box anymore.

Now then, there are those that work in NASA and have been working on these things for decades, and that last statement might almost be a slap in the face to their hard work. I don’t doubt for a second that they have learned all kinds of wonderful things, things which have not only helped the space program, but things which are also saving lives here on earth in the healthcare industry. Any time we do this sort of research, we learn more about the human body, and the human biosystem.

There was an interesting article in SpaceDaily – Your Portal to Space” which was filed under the category of; Space Medicine, and article was titled; “Antibody Production Gets Confused During Long-Term Spaceflight,” by Staff Writers in Bethesda, MD published on May 20, 2011. The article stated;

“Antibodies produced in space are less effective than those produced on terra firma. Reduced effectiveness of antibodies makes astronauts more susceptible to illness, while increasing the danger posed by bacteria and viruses likely to coexist with wayfaring astronauts.”

Obviously, a weakened immune system is a real problem in space, much more than it is here on Earth. What the researchers found was that “the antibodies generated by the group immunized in space was decreased. The spaceflight conditions alter the immune system and its ability to protect against infections and tumors, posing a serious risk for astronauts.”

Okay so, let me throw out some thoughts here if I might specifically, “WHAT IF” – yes, I know big words, but what if the anti-body production in long-term space flight had to do with light, circadian rhythm, and the Earth’s frequency? What if those exact conditions were exactly mimicked during long term space flight, along with some artificial gravity scheme?

Yes, these are the questions I believe we need to address when it comes to long-term space flight. Most are, but when it comes to this particular problem, it seems these are things we should be asking ourselves.

What about the human innate evolutionary bonding to the extremely low frequencies of planet Earth, the planet has a specific resonance too. Surely, the human biosystem along with all its symbiotic relationships will work better and correctly if they are shielded from the radiation and have available the optimized conditions they’ve evolved with. Please consider all this and think on it, let’s get this problem solved so we can von voyage to distant stars.